News

Skin cancer risk greater for men than for women

12-Apr-07

Men at greater risk of skin cancer than women
Inherent gender differences may be responsible for the higher rate of non-melanoma skin cancer in men than women, according to US research.

Previous studies have shown that men are up to three times as likely as women to develop squamous cell carcinoma.

In the past, this disparity was thought to be the result of lifestyle differences since men were believed to spend more time in the sun and use less sun protection than women.

But researchers have now shown that men may be more vulnerable to cancer than women following the same amount of ultraviolet (UV) exposure.

The study tested the effect of chronic exposure to UVB light on male and female mice. UVB is the part of the light spectrum that causes sunburn and contributes to the development of skin cancer.

A group of six male and six female mice were exposed to a fixed dose of UVB radiation three times a week for 16 weeks.

The researchers found that the male mice had a worse tumour prognosis than the females.

The males developed tumours two weeks earlier than the females, they had 50 per cent more tumours and these were on average 43 per cent larger.

In addition, 39 per cent of the tumours in the male mice were malignant compared with 18 per cent in the females, and 15 per cent of tumours in the males were fully invasive squamous cell carcinomas compared to just 3 per cent in the females.

Comments

Only registered users may comment. Log in now or register for a free account.

Login to comment


forgotten your password?

Quick search - use * for an abbreviated search, eg nico*

 
 

Healthcare Republic Forums

 

Registrar

RCGP Curriculum - 15.8 Respiratory Problems

This section of our curriculum guide refers to statement 15.8, Respiratory Problems, produced by the... Read more

RCGP Curriculum - 15.10 Skin Problems

This section of our curriculum guide refers to statement 15.10, Skin Problems, produced by the Royal... Read more

RCGP Curriculum - 13 Care of People with Mental Health Problems

This section of our curriculum guide refers to statement 13, Care of People with Mental Health Probl... Read more

Show all articles

 

Latest Clinical Articles

Chronic constipation

Contributed by Dr Naila Arebi, consultant gastroenterologist, St Mark's Hospital, Harrow, and The Lo... Read more

Sexually transmitted infections

Contributed by Dr Alan McOwan, lead clinician, Victoria Clinic for HIV and Sexual Health, London. Read more

Pemphigus

Contributed by Dr Sacha Goolamali, dermatology specialist registrar and Dr Rachael Morris-Jones, con... Read more

Show all clinical articles

MIMS Product News

New drug - NuvaRing

A non-daily, low oestrogen contraceptive utilising a vaginal delivery system. Read more

New drug - Siklos

Nordic Pharma has launched Siklos (hydroxycarbamide) for the prevention of recurrent painful vaso-oc... Read more

New drug - Bridion

Schering-Plough has launched Bridion (sugammadex) for the reversal of neuromuscular blockade induced... Read more

Jobs

 

Job of the Week