News

Family history 'improves' colorectal cancer survival

06-Jun-08

Survival odds from advanced colorectal cancer are better if you have a family history of the disease, US research suggests.

The findings come from a study of 1,087 patients with stage 3 colon cancer receiving chemotherapy, almost 18 per cent of who had one or more first-degree relatives who had suffered from the disease.

Over a median follow-up of five years and seven months, 29 per cent of those with a family history of colorectal cancer died or suffered from cancer recurrence, compared with 38 per cent of those without.

Separating the two risk factors out, the researchers found that having a family history of colorectal cancer reduced the risk of cancer recurrence by 26 per cent and death by 25 per cent.

Further analysis showed that the more relatives with colorectal cancer a patient had, the stronger the benefit. For example, those with two or more affected relatives had a 51 per cent lower risk of cancer recurrence or death than those without a family history.

rachel.liddle@haymarket.com

Comment below and tell us what you think

Comments

Only registered users may comment. Log in now or register for a free account.

Login to comment


forgotten your password?

Healthcare Republic Forums

 

Registrar

nMRCGP exam update - Evidence for aspirin use

Current situation. Read more

RCGP curriculum - Introducing the GP curriculum

Dr Ben Riley and Dr Jayne Haynes explain what the curriculum is and why it is necessary. Read more

Alcohol problems in young people

Greater awareness of drinking problems is needed, say Professor Eileen Kaner and Ruth McGovern. Read more

Show all articles

 

Latest Clinical Articles

Altitude-related illness

Contributed by Dr Matthew Litchfield, GP, Nottingham and Dr James Milledge, retired consultant respi... Read more

Clinical Review - Subfertility in women

Contributed by Mr David Walker, consultant obstetrician and gynaecologist at the Royal United Hospit... Read more

Stable angina pectoris

Contributed by Dr Unni Krishnan, clinical research fellow in cardiology at the Glenfield Hospital, L... Read more

Show all clinical articles

MIMS Product News

New drug - Volibris

GSK has launched Volibris (ambrisentan) for the treatment of pulmonary arterial hypertension (WHO Cl... Read more

New drug - Thymoglobuline

Thymoglobuline is an immunosuppressant for the prophylaxis of graft rejection in renal or heart tra... Read more

New drug - Tyverb

Tyverb (lapatinib) is an oral antineoplastic agent that may provide women with an alternative option... Read more

Jobs

 

Job of the Week