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Treatment hope for meningitis
01-Mar-07
A treatment for meningitis infection could be developed after scientists identified enzymes produced by the meningitis bacteria to evade attack by the human immune system.
A treatment for meningitis infection could be developed after scientists identified enzymes produced by the meningitis bacteria to evade attack by the human immune system.
Two endonuclease enzymes, which cut DNA at specific points, appear to protect the genetic material of Neisseria meningitidis from oxidative damage caused by human white blood cells. This UK study focused on AP endonuclease (NApe) and 3-phosphodiesterase (NExo), which were identified from the meningitis genome.
Identifying a way to disable these enzymes would render the N. meningitidis unable to repair itself.
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